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| - Britain on Monday appealed for a person infected with a powerful Covid-19 strain from Brazil to come forward as experts fretted about its impact on new vaccines. The public appeal came a week before England is due to start slowly unwinding its third Covid lockdown, with progress hinging on the vaccines' ability to curtail the pandemic. The variant that emerged in Manaus, northern Brazil, has been detected in six people in the UK, one of whom cannot be located after they failed to fill in their contact details on a form after taking their coronavirus test. "We are working with several data points to try and locate them, not least, of course, to try and highlight anyone who has had a test on (February) 12 to come forward if they haven't had a result," vaccines minister Nadhim Zahawi told BBC television. He said community-wide "surge testing" was starting in South Gloucestershire, western England, after two of the Manaus cases were confirmed there. Prime Minister Boris Johnson cautioned there was no evidence yet that vaccines were ineffective against the latest Brazilian variant, and other new strains that have emerged around the world. "We don't have any reason at the present time to think that our vaccines are ineffective against these new variants of all types," he said during a visit to a school that is preparing to reopen next week. However, experts warned that based on data from Brazil, the variant was both more transmissible and better at evading antibodies than the UK's predominant strain which emerged in the southeastern county of Kent last September. Danny Altmann, professor of immunology at Imperial College in London, said the public should feel "somewhat worried but not total panic" about the emergence in Britain of the Manaus variant. "It's not that all immunity is gone, it's that the vaccines look so much less potent, so there'll be more people who have low antibody responses where it can break through and get affected," he told Times Radio. "It all comes back much harder." In mid-January, Britain banned flights from South America including Brazil, and introduced a mandatory hotel quarantine system a month later. The new cases arrived on a flight from Sao Paulo via Zurich around February 10, just prior to its rollout, triggering complaints from opposition parties about the delay in its implementation. Johnson defended his government's handling of the country's borders. "We moved as fast as we could to get that going," he said. Britain has Europe's highest death toll from the Covid pandemic. On Sunday the government said it had given more than 20 million people at least one dose of a coronavirus vaccine, providing some hope that the end is in sight -- unless new strains take hold. Next Monday, schools across England are due to reopen to pupils for classroom teaching as part of a staggered return to normality over the coming months. jit/jj/jxb
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