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| - Here are the latest developments in the coronavirus crisis: A western Japanese city cancels the Tokyo Olympics torch relay over spiking cases, sparking fresh fears about whether the pandemic-postponed Games should go ahead with just 100 days until the opening ceremony. The head of the Tokyo Medical Association warns that holding the event this summer will be "really difficult" given the spike in cases across the country. Hundreds of people test positive in India at the site of the world's biggest religious festival as huge crowds of mostly maskless Hindu devotees descend on the River Ganges. Thousands of police patrol the empty streets of the Bangladesh capital Dhaka -- normally jammed with some of Asia's worst gridlock -- as the government enforces a strict nationwide lockdown to combat a deadly new wave. Russian President Vladimir Putin says he has received the second dose of a vaccine and hopes Russians follow his example. Pilgrims immunised against Covid-19 circle Islam's holiest site in Saudi Arabia's Mecca city and enter the Grand Mosque with masks as they perform the year-round umrah pilgrimage on the first day of the fasting month of Ramadan. Pfizer has "ramped up production" of its vaccine and can deliver 10 percent more doses than expected to the US by the end of May, says its CEO. People aged under 60 who have been given a first dose of the Oxford-AstraZeneca vaccine in Germany will receive a different jab for their second dose, federal and regional health ministers agree. Britain's biggest retailer Tesco announces a six-fold surge in annual net profit after the supermarket giant exited Asian markets and was allowed to stay open during lockdowns. US biotech company Moderna announces its Covid-19 vaccine is 90 percent effective against all forms of the disease and 95 percent effective against severe disease -- a slight decrease from a figure published in December. Australia will dispatch its trade minister on a mission to Europe amid a dispute over more than three million doses of a EU-manufactured shot which Canberra has purchased but not received. Among Covid patients a lack of exercise is linked to more severe symptoms and a higher risk of death, according to a study of nearly 50,000 people infected with the virus and reported in the British Journal of Sports Medicine. At least 2,961,387 people have died of Covid-19 around the world since the outbreak emerged in China in December 2019, according to a tally from official sources compiled by AFP. The United States is the worst-affected country with 563,446 deaths, followed by Brazil with 358,425, Mexico with 210,294, India with 172,085 and Britain with 127,123. burs-eab/spm
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