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| - Here are the latest developments in the coronavirus crisis: The virus has claimed at least 1,263,890 lives worldwide since it first emerged in China late last year, according to an AFP tally on Tuesday at 1100 GMT based on official sources. More than 50,907,779 cases have been registered across the globe. The United States is the worst-affected country with 238,251 deaths from 10,110,552 cases. After the US, the hardest-hit countries are Brazil with 162,628 deaths, India with 127,059, Mexico with 95,255 and the United Kingdom with 49,063 deaths. The European Union says it is close to signing a contract with Pfizer and BioNTech for 300 million doses of a future new vaccine but that the Medicines Agency is reviewing its safety. The World Health Organization chief hails as "encouraging" the vaccine that is 90 percent effective in preventing infections in ongoing Phase 3 trials. US, Japan and Hong Kong markets all open higher on news of the promising vaccine. The US Food and Drug Administration grants emergency approval to a synthetic antibody treatment after the drug was shown to reduce the risk of hospitalisation and emergency room visits. Brazil says it has suspended clinical trials of a Chinese-developed vaccine after an "adverse incident" involving a volunteer recipient. A leading health expert warns the situation in Italy is "largely out of control", as doctors called for a new national lockdown to counter a surge in cases. Italy coach Roberto Mancini calls up three more players as cover for his squad which has been hit by withdrawals ahead of their Nations League games. Mancini himself is in quarantine with the virus and will work remotely at least until the weekend. Denmark and Sweden will be without UK-based players for their friendly match in Copenhagen on Wednesday due to travel restrictions imposed by the UK government over a new coronavirus strain linked to Danish mink farms. A Greek football club slams three players for a rooftop "coronavirus party" in Athens that local media say involved a DJ and 40 guests, some of whom locked themselves in the toilets to avoid being found. Britain's unemployment rate jumps to 4.8 percent as the pandemic destroys a record number of jobs, official data shows. The city of Duesseldorf is forced to lift an order for residents to wear masks after a citizen successfully sues against the blanket rule. Palestine Liberation Organisation secretary general and chief negotiator Saeb Erekat dies of coronavirus complications at the age of 65. Ukrainian President Volodymyr Zelensky tests positive, his office says, adding that he "is feeling well", will self-isolate and continue to perform his duties. Prime Minister Benjamin Netanyahu inaugurates a rapid testing centre at Israel's main international airport meant to ease travel in and out of the country. US President-elect Joe Biden says masks are not a "political statement" and names the scientists who will lead his administration's response to the pandemic. Two more people close to Donald Trump test positive: Housing and Urban Development Secretary Ben Carson, 69, and aide David Bossie, 55. Spanish golfer Sergio Garcia, the 2017 Masters champion, withdraws from the 84th Masters after announcing he has tested positive. At WHO's main annual assembly chief Tedros Adhanom Ghebreyesus calls on everyone to keep fighting warning that while we may be sick of the pandemic, the virus is "not tired of us". Collins Dictionary selects "lockdown" as the Word of the Year in 2020 because it has become synonymous with the experience of populations across the world. burs-nrh/eab/bp
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