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| - European stock markets were mostly flat Monday while Wall Street opened in positive territory, as traders weighed up coronavirus vaccine hopes against the reimposition of containment measures in several countries. Trials on one of the most advanced vaccines resumed at the weekend after pausing when a volunteer fell ill. British regulators gave AstraZeneca and the University of Oxford the go-ahead to push on following an investigation, while the drug group said it remained hopeful the vaccine would still be available "by the end of this year, early next year". Investors' mood "has been heartened somewhat by the news that AstraZeneca resumed its Covid-19 vaccine trial," said Briefing.com analyst Patrick O'Hare. He pointed also to Pfizer's statement that it should have enough safety data on its vaccine candidate by late October, and Merck's announcement of human trials for its inoculation. But in the short term, the WHO's European chief Hans Kluge told AFP Monday that the autumn will be "tougher" with "more mortality" from Covid-19. Governments across the world are already seeing worrying surges in new infections, forcing Israel to introduce a three-week lockdown. Britain, France, Austria and the Czech Republic were among European countries reporting surges. After a spate of local lockdowns this month, new government restrictions come into force across England on Monday, limiting social gatherings to no more than six people. It comes as Britain's parliament finds itself arguing about Brexit again, with threats of rebellion and resignations over Prime Minister Boris Johnson's plan for a new law that would break his EU divorce treaty. The contentious legislation, unveiled last week, would override the divorce deal the UK struck with the EU last year in several key areas related to Northern Ireland. "The Brexit vote should ensure volatility for the pound and FTSE," noted Joshua Mahony, senior market analyst at IG trading group. Sterling was up slightly against both the dollar and the euro, although it was far from making up the 3.6 percent it shed last week on Brexit concerns. In Asian stocks trading, Tokyo closed higher thanks to a surge of nine percent in SoftBank shares after the Japanese group said it was selling British chip designer Arm to NVIDIA of the US for up to $40 billion. Major deals like the Arm-NVIDIA tie-up and an anticipated sale of the US operations of video sharing service TikTok to Oracle "have a lot to do" with the positive mood on markets, O'Hare said. Treasury Secretary Steven Mnuchin said Monday that his office had received a proposal from Oracle over the weekend after Microsoft's bid was rejected. The offer must now be handled by a government panel that reviews foreign transactions for national security concerns. Meanwhile "the market doesn't seem to be holding out much hope right now" that Washington will agree on a new round of stimulus to fight the economic impact of the coronavirus before November's elections, O'Hare added. Some reassurance could come from a Fed meeting next week, with policymakers likely to issue "a reminder that it stands ready to provide more policy support if necessary," he said. London - FTSE 100: DOWN 0.2 percent at 6,021.36 points Frankfurt - DAX 30: DOWN 0.1 percent at 13,185.21 Paris - CAC 40: UP 0.3 percent at 5,020.21 EURO STOXX 50: FLAT at 3,316.61 New York - Dow: UP 0.6 percent at 27,839.19 Tokyo - Nikkei 225: UP 0.7 percent at 23,559.30 (close) Hong Kong - Hang Seng: UP 0.6 percent at 24,640.28 (close) Shanghai - Composite: UP 0.6 percent at 3,278.81 (close) Pound/dollar: UP at $1.2896 from $1.2800 at 2050 GMT on Friday Euro/pound: DOWN at 92.11 pence from 92.52 pence Euro/dollar: UP at $1.1878 from $1.1843 Dollar/yen: DOWN at 105.71 yen from 106.10 yen West Texas Intermediate: DOWN 0.6 percent at $37.10 per barrel Brent North Sea crude: DOWN 0.7 percent at $39.56 per barrel dan-bcp/tgb/wai
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