About: http://data.cimple.eu/news-article/cffd2b48f127241828279770446108d9204415179a503276d38d87b3

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: http://data.cimple.eu/news-article/cffd2b48f127241828279770446108d9204415179a503276d38d87b3 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:NewsArticle, within Data Space : data.cimple.eu associated with source document(s)

Attributes	Values
rdf:type	schema:NewsArticle
schema:articleBody	Doctors in Japan have successfully transplanted liver cells derived from embryonic stem cells into a newborn baby, in a world first that could provide new treatment options for infants. The newborn was suffering from urea cycle disorder, where the liver is not capable of breaking down toxic ammonia. But the six-day-old was too small to undergo a liver transplant, generally not considered safe until a child weighs around six kilogrammes (13 pounds) at around three to five months old. Doctors at the National Center for Child Health and Development decided to try a "bridge treatment" until the baby was big enough, injecting 190 million liver cells derived from embryonic stem cells (ES cells) into the blood vessels of the baby's liver. Following the treatment, "the patient did not see an increase in blood ammonia concentration and was able to successfully complete the next treatment", namely a liver transplant, the institute said in a press release. The baby, whose sex has not been disclosed, received a liver transplant from its father and was discharged from the hospital six months after birth. "The success of this trial demonstrates safety in the world's first clinical trial using human ES cells for patients with liver disease," the institute said. It noted that in Europe and the United States, liver cells are often available after being removed from brain-dead donors, but the supply in Japan is more limited. That has created difficulties in managing the health of small children as they wait to grow big enough for liver transplants. ES cells are harvested from fertilised eggs and using them in research has raised ethical issues because embryos are destroyed subsequently. The national institute is one of two organisations in Japan allowed to establish ES cells to study new medical treatments. It works with fertilised eggs whose use has been approved by both donors having already completed fertility treatment, according to the institute. mis/sah/jah
schema:headline	Japan newborn gets liver stem cells in world first
schema:mentions	Liver disease Embryonic stem cell Management information system Liver transplantation Ammonia Stem cell Clinical trial Bridge Europe Japan United States Urea cycle Assisted reproductive technology
schema:author	http://data.cimple.eu/organization/1f0054d541e000623a2c1e561a247c073ef6328e8be9ffafda7b3fcd
schema:datePublished	2020-05-21 (xsd:date)
http://data.cimple...sPoliticalLeaning	other political leaning
http://data.cimple...logy#hasSentiment	negative sentiment
http://data.cimple...readability_score	85 (xsd:integer)
http://data.cimple...tology#hasEmotion	happiness

Faceted Search & Find service v1.16.115 as of Oct 09 2023

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3238 as of Jul 16 2024, on Linux (x86_64-pc-linux-musl), Single-Server Edition (126 GB total memory, 3 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software